Tag Archives: Addiction

addiction

• Scope •Biological basis of addiction •Neurotransmitters and circuits •Transition from use to compulsion •Excludes: •Individual mechanism of drugs or their pharmacology •Genetics and epigenetics •Clinical issues such as mechanisms of tolerance, withdrawal etc •No issues regarding treatment or medications Loading… The neurobiology of addiction Model of interacting circuits in which disruptions contribute to compulsive-like […]

Of substance | Deccan Herald

Human beings, since time immemorial, have a natural urge to ‘feel different’ periodically. It has been called the ‘fourth drive’ after food, sex and sleep. Children discover the experience quite early when they playfully spin round and round at an increasing speed, till they feel a head rush. Adults do it by taking mind-altering substances or […]

Addiction

  2017.1.118.40 Adoption Date: April 12, 2011 Public Policy Statement: Definition of Addiction PDF Short Definition Frequently Asked Questions (FAQs) Short Definition of Addiction: Addiction is a primary, chronic disease of brain reward, motivation, memory and related circuitry. Dysfunction in these circuits leads to characteristic biological, psychological, social and spiritual manifestations. This is reflected in […]

Evidence-Based Treatments of Addiction

Charles P. O’Brien FOCUS 2011;9:107-117.   Both pharmacotherapy and behavioural treatment are required to relieve the symptoms of addictive disorders. This paper reviews the evidence for the benefits of pharmacotherapy and discusses mechanisms where possible. Animal models of addiction have led to some medications that are effective in reducing symptoms and improving function but they […]

drug dependence

_ _ _ _ Some people who use drugs use large enough amounts often enough and long enough to become dependent. Definitions A single definition for drug dependence is elusive. Concepts that aid in defining drug dependence are tolerance and psychologic and physical dependence. Tolerance describes the need to progressively increase the drug dose to […]