Monthly Archives: March 2020
Trials
Landscape analysis of therapeutics as 21st March 2020 Product type and candidate Description Licensed for Licensed dose Route of administration Currently being trialled COVID-19? Status of clinical development for Coronaviruses Proposed dose for COVID-19 Status of clinical development for other relevant conditions Re-purposed/off label Corticosteroids Steroid hormones   Various Various  Inhaled, parenteral injectables […]
Developing Covid-19 Vaccines at Pandemic Speed g
 Developing Covid-19 Vaccines at Pandemic Speed The need to rapidly develop a vaccine against SARS-CoV-2 comes at a time of explosion in basic scientific understanding, including in areas such as genomics and structural biology, in the recent outbreaks in the Democratic Republic of Congo. The vaccine received conditional marketing authorization from the European Medicines […]
Reuse masks
N95 EXTENDED USE, REUSE AND STERILISATION Courtes my friend Dr Shiv Kumar Singh, sr Intensivist 🇬🇧 UK In the present situation of shortage of PPE, this question is often asked. Please read till the end This is based on CDC recommendations and some research on sterilisation. I hope this information will be helpful to everyone […]
Management. Covid
 Government of India Ministry of Health & Family Welfare Directorate General of Health Services (EMR Division) Guidelines on Clinical Management of COVID – 19 This document is intended for clinicians taking care of hospitalised adult and paediatric patients of COVID – 19. It is not meant to replace clinical judgment or specialist consultation but […]
Masks
Understanding about the various types of commonly used masks and clarify the proper indications of use… Q1 … What are the common types of masks Ans… 1 Cloth mask 2 Surgical mask Q2… What are the Respirators Ans. N- 95 N- 99 N- 100 are the respirators Q3.. what is the difference between mask and […]
Addictive Disorders in India
 CLINICAL PRACTICE GUIDELINES on Newer and Emerging Published by Indian Psychiatric Society, India Editors Debasish Basu | P.K. Dalal | Y.P.S. Balhara  Indian Psychiatric Society Specialty Section on Substance Use Disorders CLINICAL PRACTICE GUIDELINES on Newer and Emerging Addictive Disorders in India  Indian Psychiatric Society Specialty Section on Substance Use Disorders 2016 […]
Mental health
The Duke and Duchess of Cambridge have given their support to a campaign to protect people’s mental health during the coronavirus outbreak. Public Health England (PHE) has launched new advice on wellbeing. The guidance encourages people to keep in contact with family and friends by phone or social media and stick to a regular routine […]
Correlation between universal BCG vaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study
medRxiv preprint doi: https://doi.org/10.1101/2020.03.24.20042937. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license . Aaron Miller, Mac Josh Reandelar, Kimberly Fasciglione, Violeta Roumenova, Yan Li, and Gonzalo H. Otazu* […]
chances
Do Indians have better chances of survival from COVID 19 epidemic? The impact of epidemic depends on three factors: the infectivity and virulence of the agent, the suspecptibity of the host, and the environment favorability of the agent. That means simply, if the infectivity is high, it’s going to attack more people, but if the […]
Zhang
Summary of today’s webinar session with Dr. WenHong Zhang, the chair of the Society of Infectious Diseases of China Medical Association. -There about 7000 attendees, mostly United States listeners, including Stanford Health Care, Santa Clara County hospitals, and New York City hospitals and also India and London . Here are some notes. -Predicted number of […]
SUGGESTED READING IF YOU’RE APPLYING FOR COVID REDEPLOYMENT
This is a copied post from another page and is a very good overview of the clinical presentation written by an A and E consultant in the US. Is identical to our experience in London. An experience from the field……… I am an ER MD in New Orleans. Class of 98. Every one of my […]
पूरे भारत में कई लोग डॉक्टर्स की बंद क्लीनिक पर सवाल उठा रहे है ,यह है मेरे विधिवत जवाब
:- 1.सारे बड़े अस्पताल और उनकी आकस्मिक सुविधाएं चालू है हमेशा से , लोकडाउन की अपील प्रधान मंत्री जी ने की थी इसलिए हमने आप की सुरक्षा के लिए आम ओपीडी बंद की जो की कई सरकारी अस्पताल भी कर चुके है। 2.हमें आपकी सेवा के लिए उपकरण चाहिए जैसे पी पी ई मतलब करोना […]
Summary points of Telemedicine CME held in NIMHANS
1. Patient requesting for phone consultation is consent implied. 2. If we are giving an option for phone consultation patient should give it in writing via mail, message or voice or video message as explicit consent is needed. 3. Mode of consultation in Telemedicine (like video or audio) can be decided by us. 4. New […]
Who lives. Who dies
How do doctors and hospitals decide who gets potentially lifesaving treatment and who doesn’t? A lot of thought has been given to just such a predicament, well before critical shortages from the coronavirus pandemic. “It would be irresponsible at this point not to get ready to make tragic decisions about who lives and who dies,” […]
Covid 19 update
Hope all of you are staying safe ,while trying to save the community. NSAIDs should not be used . No steroids (unless COPD/Asthma patients requiring absolutely ) Ok to continue ACEI/ARB,no need to stop them for suspicious or confirmed covid cases . Look for troponin elevation in COVID 19 ,which generally signifies myocarditis with electric […]
Covid prevention handbook
     Copyright © 2020 Hubei Science and Technology Press Originally published by Hubei Science and Technology Press, Wuhan, China. The world translation rights is exclusively represented by Rightol Media (copyright@rightol.com) Chief Editor: Wang Zhou Reviewed by Yongjian Xu Foreword by Nanshan Zhong Translated by Shan Zhu, Qing Chen, Jun Li All […]
Guidelines for Isolation Ward and Infection Control in secondary healthcare facilities: COVID-19
   Version-QI/NHSRC/00-27/3/2020 Scope and Objectives The scope of these guidelines is limited to a Secondary Healthcare setting that includes DHs, SDHs and CHCs. These simple and practical guidelines intents to serves the following purpose:- To establish isolation facility at the level of Secondary health care facility DHs, SDHs and CHCs. To Guide health […]
Do Indians have better chances of survival from COVID 19 epidemic?
The impact of epidemic depends on three factors: the infectivity and virulence of the agent, the suspecptibity of the host, and the environment favorability of the agent. That means simply, if the infectivity is high, it’s going to attack more people, but if the virulence is high, it will kill more people without being able […]
A medical system on life support
ener HEALTH By Jamie Ducharme When Dr. mark Lewis has To give a cancer patient bad news, he usually o ers a hug or a hand to hold. The idea of doing so by phone felt heartbreakingly imper- sonal, he says. But in the face of the COVID-19 pandemic, the Salt Lake City–based gastrointestinal oncologist […]
Covid19
 Note: this is a compressed version for quick downloading, a higher resolution standard version is also provided Handbook of COVID-19 Prevention and Treatment The First Affiliated Hospital, Zhejiang University School of Medicine Compiled According to Clinical Experience       Editor’s Note: Faced with an unknown virus, sharing and collaboration are […]
Passive immunity
Blood from people who recover from coronavirus could provide a treatment Plasma is being studied as a way to fight off the virus A transmission electron micrograph of SARS-CoV-2 virus particles, isolated from a patient. (NIAID/National Institutes of Health Handout/EPA-EFE/Shutterstock) By Carolyn Y. Johnson and Ben Guarino March 28, 2020 at 12:00 a.m. GMT+5:30 PLEASE […]
गौरैया
चीन में आज से 60 वर्ष पूर्व भी किया था एक मानवीय भूल और आज फिर उसी गलती को दोहरा दिया आइए जानते हैं ऐसा क्या हुआ था चीन में जिससे चार करोड़ लोगों की जान गई थी चिड़िया! चीं चीं करने वाली घरेलू चिड़िया… और 3 करोड़ से ज़्यादा इंसानी मौतें! एक भयावह ऐतिहासिक […]
Covid medicines
*Which medicines to give in COVID-19 and why?* 1. Antimicrobials- Post viral pneumonias have about 20% co-infection with bacteria. Give Gram negative and cover staph. 2. Paracetamol- The range of temperature in COVID was recorded as 37.8–38.9C. Paracetamol is effective antipyretic without almost any harm upto a dose of 4 gm/day in adults. Besides fever […]
Evolution, human-microbe interactions, and life history plasticity
Series  Evolutionary public health 3 Graham Rook, Fredrik Bäckhed, Bruce R Levin, Margaret J McFall-Ngai, Angela R McLean A bacterium was once a component of the ancestor of all eukaryotic cells, and much of the human genome originated in microorganisms. Today, all vertebrates harbour large communities of microorganisms (microbiota), particularly in the gut, and […]
Q and A
Evidence-based answers to questions that doctors commonly ask about COVID19. Dr Rajeev Jayadevan, 26 March 2020 Note: 1. This is a scientific update written specifically for doctors. It is NOT meant for circulation among the general public. Those who do not have a medical background and adequate knowledge of statistics SHOULD NOT be reading this, […]
Lab findings in corona
Dr. Sudhir Mehta discusses the current hot topics concerning COVID-19- lymphocyte count as a marker for the illness plus other significant lab findings to watch out for, and the use of drugs- hydroxychloroquine and azithromycin. For our comprehensive coverage and latest updates on COVID-19 click here. Lymphocyte count: Is it a prognostic marker in COVID-19? […]
COVID-19 & Protagoras Paradox
Over 2000 years ago, in Greece, there was a lawyer named Protagoras. A young student, Euthalos, requested to apprentice under him, but was unable to pay the fees. The student struck a deal saying, “I will pay your fee the day I win my first case in the court”. Teacher agreed. When the training was […]
Make your own hand rub
GUIDE TO LOCAL PRODUCTION: WHO-RECOMMENDED HANDRUB FORMULATIONS                                                 […]
Will coronavirus pandemic diminish by summer?
Qasim Bukhari1 * , Yusuf Jameel2 * 1 McGovern Institute for Brain Research, Massachusetts Institute of Technology (MIT), Cambridge, USA 2 Department of Civil and Environmental Engineering, Massachusetts Institute of Technology (MIT), Cambridge, USA Funding: This work is supported by Abdul Latif Jameel Clinic for Machine Learning in Health (J-Clinic) Abstract The novel coronavirus (2019-nCoV) […]
High Temperature and High Humidity Reduce the Transmission of COVID-19
High Temperature and High Humidity Reduce the Transmission of COVID-19 Jingyuan Wang, Ke Tang, Kai Feng and Weifeng Lv* March 9, 2020 Abstract. This paper investigates how air temperature and humidity influence the transmission of COVID-19. After estimating the serial interval of COVID-19 from 105 pairs of the virus carrier and the infected, we calculate […]
Covid. What to expect clinically
Summary of today’s webinar session with Dr. WenHong Zhang, the chair of the Society of Infectious Diseases of China Medical Association. -There about 7000 attendees, mostly United States listeners, including Stanford Health Care, Santa Clara County hospitals, and New York City hospitals and also India and London . Here are some notes. -Predicted number of […]
Covid 19
To the Editor — Since the first reports of novel pneumonia (COVID-19) in Wuhan, Hubei province, China1,2, there has been considerable discussion on the origin of the causative virus, SARS-CoV-23 (also referred to as HCoV-19)4. Infections with SARS-CoV-2 are now widespread, and as of 11 March 2020, 121,564 cases have been confirmed in more than […]
Coronavirus: Why You Must Act Now
Politicians, Community Leaders and Business Leaders: What Should You Do and When? Tomas Pueyo Mar 10 · 26 min read Updated on 3/19/2020. This article has received over 40 million views in the last week. Over 30 translations at the bottom. The next article is ready: Coronavirus, The Hammer and the Dance. If you agree […]
Coronavirus in India: Make or Break
Mohak Gupta Mar 23 · 15 min read Coronavirus. A medical professional would know how the meaning of this word has changed drastically in the past 3 months. From being the virus that causes ‘common cold’, to today- where it has killed over 13000 people worldwide, and it’s just getting started. The novel coronavirus (2019-nCov […]
Predictions for covid
Summary for Policy 1. Delays in testing are seriously reducing the ability of the population to protect itself. This is the most important way in which we can contain the epidemic. An increase in the official number of detected cases in the short term could encourage the population to take distancing more seriously and will […]
Bill Gates: “The Corona Virus… is sent to remind us of the important lessons that we seem to have forgotten
But multi-billionaire Gates, 64 – who donated £85 million to combat the virus last month – believes that despite the chaos, there is ‘a spiritual purpose behind everything that happens’. In an open letter, entitled ‘What is the Corona/ Covid-19 Virus Really Teaching us?’, he wrote: ‘A SPIRITUAL PURPOSE’ “I’m a strong believer that there […]
Update on covid
COVID19 for India Updates March 24, 2020 IndiaSIM • We use IndiaSIM, a well-validated agent-based model of the Indian population. This has been published widely over many years and has been used for government decision-making including by NTAGI for vaccine introduction. A brief summary of the model is attached. The model describes the actual Indian […]
Hcqs in covid
Dr. Anant Patil writes on drugs chloroquine, hydroxychloroquine, and azithromycin, all three of which have been under the spotlight now, for their roles in the treatment of COVID-19. For our comprehensive coverage and latest updates on COVID-19 click here. Chloroquine is a well-established anti-malarial drug with anti-inflammatory action. It is also used in the treatment […]
Devi Shetty
How MCI can save the country: Tough Covid-19 battle can only be won by our young doctors and nurses. We need many more of them March 26, 2020, 2:00 AM IST Devi Shetty in TOI Edit Page | Edit Page, India | TOI First, I would like to congratulate Prime Minister Narendra Modi for taking […]
Temporal separation
COVID-19: AVOIDING THE SECOND BLOW A PLEA FOR MANDATORY TEMPORAL SEPARATION IN ESSENTIAL SERVICES AS AN ADJUNT TO SPATIAL SEPARATION IN OVERALL PUBLIC INTEREST 24/3/2020 Dr Rachita Chopra MBBS, DNB (General Surgery), MRCSEd, ATLS Instructor INTRODUCTION Central government has brought into effect national lockdown in • view of COVID-19 pandemic The rationale for national lockdown […]
Telemedicine Practice Guidelines
BOARD OF GOVERNORS In supersession of the Medical Council of India Appendix 5 Enabling Registered Medical Practitioners to Provide Healthcare Using Telemedicine    March 2020  These Guidelines have been prepared in partnership with NITI Aayog 2 S. No. 1. Description Background TABLE OF CONTENT Page No. 7 10 2. 4. Definitions […]
CORONAVIRUS CRISIS
Interview: ‘Suppression won’t work in India. Slow down the coronavirus. This will be a long haul’ One of India’s most renowned epidemiologists cautions against unsustainable lockdowns and says community participation is the key to fight the disease. MOBILE & TABLET ONLY META Arunabh Saikia Mar 23, 2020 · 04:38 pm END OF MOBILE & TABLET […]
High Temperature and High Humidity Reduce the Transmission of COVID-19
High Temperature and High Humidity Reduce the Transmission of COVID-19 Jingyuan Wang, Ke Tang, Kai Feng and Weifeng Lv* March 9, 2020 Abstract. This paper investigates how air temperature and humidity influence the transmission of COVID-19. After estimating the serial interval of COVID-19 from 105 pairs of the virus carrier and the infected, we calculate […]
Art of caring
 FOREWORD It was not until a new resident in the Emergency Department (ED) burst into tears in front of me, did I realise the toll that residency in this department takes on a residents’ overall well-being. The ED work culture is unlike any other department. Physicians have to deal with numerous responsibilities and at […]
Predictions and role of interventions for COVID-19
3/24/2020 Predictions and role of interventions for COVID-19 outbreak in India Anyone can publish on Medium per our Policies, but we don’t fact-check every story. For more info about the coronavirus, see cdc.gov.  outbreak in India Crisis Of Virus in INDia (COV-IND) COV-IND-19 Study Group Mar22·12minread The following summary was prepared by the COV-IND-19 […]
Hantavirus
An orthohantavirus (or hantavirus) is a single-stranded, enveloped, negative-sense RNA virus in the family Hantaviridae of the order Bunyavirales.[3] These viruses normally infect rodents, but do not cause disease in them.[3] Humans may become infected with hantaviruses through contact with rodent urine, saliva, or feces. Some strains cause potentially fatal diseases in humans, such as […]
Pahalwan ki dholak
जाड़े का दिन। अमावस्या की रात—ठंढ़ी और काली। मलेरिया और हैजे से पीड़ित गांव भयार्त शिशु की तरह थर—थर कांप रहा था। पुरानी और उजड़ी, बांस—फूस की झोपड़ियों में अंधकार और सन्नाटे का सम्मिलित साम्राज्य। अंधेरा और निस्तबधता! अंधेरी रात चुपचाप आंसू बहा रही थी। निस्त्बधता करूण सिसकियों और आहों को बलपूर्वक अपने ह्रदय में […]
The plague. Excerpts
At that moment the boy, as though bitten in the stomach, doubled up again with a high-pitched moan. He remained bent like this for several seconds, shaking and trembling convulsively, as though his frail body were bowing beneath the raging wind of the plague and cracking under the repeated blasts of fever. Once the gust […]