Monthly Archives: March 2021

Neutralizing antibodies after vaccination and Covid infection: Effect on Mutants

 Journal of American Medical Association (JAMA) Salient Features • Serum neutralizing antibodies rapidly appear after SARS-CoV-2 infection and vaccination • This study compared neutralizing antibody response of previously infected and vaccinated person against mutants. • Serum from PCR confirmed cases and also from vaccinated persons were tested with variants (Mutants) for neutralizing potential. These […]

“Ring a Ring a Roses

There is a myth that the British children’s rhyme “Ring a Ring a Roses” is all about the plague—either the Great Plague of 1665-6 or the Black Death centuries earlier—and dates from those eras. The words describe the contemporary practice in treating it, and refer to the fate so many befell. The Truth The earliest […]

The ‘Peltzman effect’

In 1975, University of Chicago economist Samuel Peltzman first described the phenomenon of compensating behavior – often termed the ‘Peltzman effect’ or in epidemiology, “risk compensation” or “risk homeostasis.” In his classic analysis of automobile safety regulation,4 Peltzman argued that federally mandated improvements in U.S. automobile safety in the 1960s (e.g., seat belts for all […]

What Is Dravet Syndrome?

Dravet syndrome is a rare, severe, and incurable epilepsy syndrome that begins in early childhood. It was previously known as severe myoclonic epilepsy of infancy (SMEI). Dravet syndrome is characterized by prolonged, multiple seizures frequently brought on by increased body temperature. A mutation of the SCN1A gene, which controls electrical signals in the brain, is […]

S N Medical college agra state of affairs

S.N. medical college is having a golden history but those days are over now. It is India’s 3rd opened medical college and have produced large number of good doctors. In Uttar Pradesh either govt. Is not taking care of this medical college or it is solely fault of S.N. contruction authority. •No drinking water facility. […]

Covid update

Recently there was a seminar about covid immunity and vaccines at JIPMER, attended by experts immunologist like Dr Amita Aggarwal (SGPGI), Dr Andrew Pollard (UK), Dr N K Arora, Dr Gagandeep Kang (Vellore) and epidemiologist like Dr Muliyel (Vellore). Based discussions held, this is what I am able to conclude: 1. Our current understanding about […]

The Heimlich Maneuver

The Heimlich Maneuver If a person is coughing forcefully, encourage continued coughing to clear the object. A person who can’t cough, speak or breathe, however, needs immediate help. Ask if they are choking and let them know you will use abdominal thrusts, also known as the Heimlich maneuver, to prevent suffocation. The procedure is not recommended for children […]

Case file

      FIFTH EDITION       CASE FILES® Psychiatry   Eugene C. Toy, MD Assistant Dean for Education Professor and Vice Chair of Medical Education Department of Obstetrics and Gynecology University of Texas Medical School at Debra Klamen, MD, MHPE Associate Dean of Education and Curriculum […]

Covishield vs covaxin

             Indian Government started the vaccination rollout on 16th January 2021 and so far around 1. 8 crore people (as of 4th March) have been vaccinated with priority to healthcare and other frontline workers. From 1st March, the drive at the private vaccination […]

*Management of antidepressant discontinuation (withdrawal) syndrome: Part one*

Antidepressant discontinuation (withdrawal) syndrome (ADS) is a relatively common and troublesome condition. For mild symptoms, education and symptomatic treatment may be enough but for moderate/severe symptoms, it will be necessary to either restart the same antidepressant or switch to fluoxetine. Educate the patient Antidepressant discontinuation symptoms can really freak out the person. So, taking the […]