Tag Archives: Substance abuse

Violence Among Mentally Ill People

Experts Discuss Factors That May Lead to Violence Among Mentally Ill People Aaron Levin While researchers are beginning to understand more about factors linking violence and mental illness, much more research needs to be done to identify individuals at risk. For years, substance use has been known as a key factor mediating the intersection of […]

Evidence-Based Treatments of Addiction

Charles P. O’Brien FOCUS 2011;9:107-117.   Both pharmacotherapy and behavioural treatment are required to relieve the symptoms of addictive disorders. This paper reviews the evidence for the benefits of pharmacotherapy and discusses mechanisms where possible. Animal models of addiction have led to some medications that are effective in reducing symptoms and improving function but they […]

benzodiazepine addication

_ _ _ _ _ _ _ Anxiolytics and sedatives (hypnotics) include benzodiazepines, barbiturates, and related drugs. High doses can cause stupor and respiratory depression, which is managed with intubation and mechanical ventilation. Chronic users may have a withdrawal syndrome of agitation and seizures, so dependence is managed by slow tapering with or without substitution […]

drug dependence

_ _ _ _ Some people who use drugs use large enough amounts often enough and long enough to become dependent. Definitions A single definition for drug dependence is elusive. Concepts that aid in defining drug dependence are tolerance and psychologic and physical dependence. Tolerance describes the need to progressively increase the drug dose to […]