Daily Archives: 08/08/2026
Bile acid sequestrants (resins)
Bile acid sequestrants (resins) — specifically colesevelam, cholestyramine, and colestipol — are the lipid-lowering agents contraindicated in severe hypertriglyceridemia because they can significantly raise TG levels. This is a well-established class effect: by interrupting enterohepatic bile acid recirculation, resins upregulate hepatic VLDL synthesis, worsening hypertriglyceridemia. They are generally contraindicated when TG ≥300–400 mg/dL and absolutely […]
deemagclinic
deemag and chest clinic 