Tag Archives: Alzheimer’s disease

A Nobel Laureate on ‘Successful Aging’ – Dr. Eric Kandel’s Epic Search for the Biological Basis of Memory

Eric R. Kandel, M.D. From The Quarterly, Winter 2012 Imagine that you are standing on a busy city street corner and you gather together the first 100 passersby who are precisely 70 years old. “In this randomly selected group, let’s assume that men and women are equally represented and that none of them appears to […]

Pomegranate Compound Could Stem Alzheimer’s

Keywords: Microglia; Neuroinflammation; NF-κB; Pomegranate; Punicalagin Scope In this study, the effects of punicalagin on neuroinflammation in LPS-activated microglia were investigated. Methods and results The ability of punicalagin to reduce the production of TNF-α, IL-6 and prostaglandin E2 was measured in culture medium using enzyme immunoassay. TNF-α and IL-6 gene expression in mouse hippocampal slices […]

generics

Sir, The press has gone hammer and tong aginst doctors.The basicassumption is the erroneous guideline of MCI which statesthat the Doctors must as far as possible write only genericbrands,.Technically all the medicines in india or most ofthem are generic as they are not made by patent holders andare therefore cheap.Still some of them are manufactured […]

vitamin D deficiencies & Alzheimer’s disease

People with moderate-to-severe vitamin D deficiencies are significantly more likely to develop Alzheimer’s disease or other forms of dementia than those who have an adequate supply of the vitamin in their body, a new study has found. Researchers, led by David J. Llewellyn at the University of Exeter Medical School, found that adults who suffered […]

The Long-Term Effects of Conventional and Atypical Antipsychotics in Patients With Probable Alzheimer’s Disease

his large longitudinal observational study revealed that a higher proportion of patients exposed to antipsychotic medications, especially conventional antipsychotics, were admitted to a nursing home or died compared with those who never took these medications. However, in time-dependent statistical models, these associations were no longer present after we adjusted for the symptoms for which the […]

Diet’s Relationship to Brain Health Provides Much Food for Thought

Clinical and Research News September 18, 2009 Jun Yan New research evidence supports a beneficial effect of a Mediterranean type of diet on preventing cognitive decline and Alzheimer’s disease in older adults, according to two studies published in the August 12 Journal of the American Medical Association. A diet low in meat and poultry and high […]

Antidepressants May Have Role in Preventing Alzheimer’s Disease, Study Suggests

Research conducted by Yvette Sheline, M.D., a professor of psychiatry at the University of Pennsylvania, and colleagues and reported in Science Translational Medicine suggests that antidepressants might someday be a long-sought weapon in the fight against Alzheimer’s disease. After older mice genetically modeled to have Alzheimer’s disease were chronically given the SSRI antidepressant citalopram, it stopped the growth […]

mentally challenging work and leisurely pursuits can delay the onset of dementia

those at higher genetic risk of developing Alzheimer’s Disease, completing more school and going on to a lifetime of mentally challenging work and leisurely pursuits can delay the onset of dementia by close to nine years, says a new study. Preventing Alzheimer’s disease — with an antidepressant Melissa Healy Cultivating both early educational attainment and […]

depression as a risk factor of heart disease?

Darrel Regier, M.D., former APA director of research, discusses APA’s involvement with the AHA’s recommendation to consider depression as a major risk factor for heart disease. Sylvia Johnson Despite publication of numerous studies and meta-analyses showing a link between depression and cardiovascular disease, the American Heart Association (AHA) has yet to formally recognize depression as […]

Cognitive Training May Bestow Long-Term Benefits for Seniors

Clinical and Research News March 20, 2014  DOI: 10.1176/appi.pn.2014.3b3 Joan Arehart-Treichel   Training elderly individuals in reasoning and speed-of-information processing tasks, but not memory, resulted in sustained or improved cognitive abilities a decade later.   A large multisite, randomized, controlled clinical trial has found that cognitive training can benefit seniors up to a decade after they’ve […]

For Now, Preventive Efforts Are Best Alzheimer’s Weapon

June 14, 2013  DOI: 10.1176/appi.pn.2013.6b10 Aaron Levin   Several factors can help maintain the brain’s health as people age, says a geriatric psychiatry expert.   “The brain undergoes a lot of wear and tear as it ages,” geriatric psychiatrist Gary Small, M.D., explained at APA’s 2013 annual meeting in May. Small has spent a career seeking […]

memory loss

_ _ _ _ Memory loss is a common complaint in the primary care setting. It is particularly common among the elderly but also may be reported by younger people. Sometimes family members rather than the patient report the memory loss (typically in an elderly person, often one with dementia). Clinicians and patients are often […]