Daily Archives: 23/04/2021

Covid hospital in delhi

Dear Friends in delhi and NCR(Please share you never know who needs help) This is to inform you that from today onward 1000 beds facility is initiated by Armed Forces w.e.f 0800 hrs today for admission of all confirmed Carona Patients, who need immediate hospitalisation. This state-of-the-art, 1000-bedded Covid Care Hospital is very close to […]

Valproate, carnitine and hyperammonemia

Therapy with valproate is associated with hyperammonemia, usually less than 2-3 times the upper limit of the reference range. It is frequent in patients on combination therapy for epilepsy. The mechanism is decreased production of mitochondrial acetyl CoA, which causes decrease in N -acetylglutamate, an activator of carbamoyl phosphate synthetase. Thus, patients with partial enzyme […]