Pharmacologic Options for Borderline Personality Disorder

Key points

The use of antipsychotics in patients with BPD can be useful for anger, impulsivity, aggression, and cognitive–perceptual disturbances.
Lamotrigine can be helpful for affective instability in mild-to-moderate BPD patients.
Omega-3 fatty acids can decrease depression, suicidality, and affective instability.
The clinical approach from the Handbook of Good Psychiatric Management is that psychotherapy is the primary treatment.
Limiting the amount of medication is a useful way to reduce the risk of overdose and suicide.

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