Thanks to 50 autopsies carried out on patients who died from COVID-19, they found that it is NOT PNEUMONIA, strictly speaking, because the virus does not kill pneumocytes of its type only but uses an inflammatory storm to create an endothelial vascular thrombosis, with the corresponding diffuse thrombosis the lung is the most affected because it is the most inflamed, but also, it produces a heart attack or stroke, and many other thrombotic diseases. In fact the protocols have left the useless antiviral therapies and have concentrated on the inflammatory and anti-clotting.
These therapies must be done immediately, even at home, where the treatment responds very well to the patients. Later they are less effective. In resuscitation, they are almost useless. If the Chinese had reported it, they would have invested in home therapy, not Intensive Care! It is a case of DISSEMINATED INTRAVASCUAL COAGUALATION (THROMBOSIS). So, the way to combat it is with antibiotics, anti-inflammatories and anticoagulates.
An Italian anatomical pathologist reports that the Pergamo hospital made a total of 50 autopsies, Milan 20; the Chinese have only made 3, which seems to fully confirm the information. Success is determined by a disseminated intravascular coagulation activated by the virus, so interstitial pneumonia would have nothing to do with this, it would have been just a big diagnostic error. In retrospect, I have to rethink these chest radiographs that were discussed a month ago as interstitial pneumonia, it could actually be fully consistent with a disseminated interstitial coagulation DICA.
People go to ICUs for thrombus, generalized venous embolism; generally, lupus. If this were the case, intubations and resuscitations would be useless if thromboembolism is not resolved first. Ventilating a lung where blood does not reach is useless. In fact, nine out of ten die because the problem is cardiovascular not respiratory. It is venous micro-thrombosis and not pneumonia that determines mortality.
Why do thrombi form? Because inflammation according to the school text induces thrombosis through a complex but well-known pathophysiological mechanism. So what the scientific literature said especially from China until the middle of March was that anti-inflammatories should not be used. Now the therapy that is being used in Italy is with anti-inflammatories and antibiotics as in influenzas, and the number of hospitalized patients has been reduced. Many deaths even in their 40s had a history of fever for 10 to 15 days, which were not adequately treated here. The inflammation destroyed everything and created the ground for the formation of thrombi, because the main problem is not the virus, but the immune reaction that destroys the cell where the virus enters. In fact, patients with rheumatoid arthritis have never been admitted to the covid departments, because they are on cortisone therapy, which is a great anti-inflammatory. That is the main reason why hospitalizations in Italy are decreasing and it is becoming a treatable disease at home. By treating it well at home, not only hospitalization is avoided but also the risk of thrombosis. It was not easy to understand, because the signs of micro-embolism have faded even in the echocardiogram.
This weekend the comparison was made of the data of 50 patients between those who breathe badly and those who do not and the situation seems very clear.
With this important finding, it would be possible to return to normal life and open the businesses closed by the quarantine, not immediately, but it is time to publish these data, so that the health authorities of each country make their respective analysis of this information and avoid more useless deaths and the vaccine may come later.
In Italy from today the protocols are changing. According to valuable information from Italian pathologists, ventilators and Intensive Care Units are not required. So we must rethink investments to adequately address this disease.