Virologists identify potential COVID-19 treatments Scientists developing inhibitors of a critical viral enzyme called C3-like protease have engineered and studied compounds that inhibit this viral enzyme. C3-like protease is an enzyme that is essential for coronaviruses to replicate and crucial to their survival. Researchers tested the antiviral compounds’ effect on SARS-CoV-2 in cultured human airway cells and tested them in a mouse model for MERS. […]

TREATMENT PROTOCOL FOR COVID19 PATIENTS (VERSION 3.0) DISCLAIMER: This Recommendation is derived from the prevailing trials published and collation of various guidelines. These guidelines would change with the evolving evidences DEFINITIONS: • ILI is defined as one with acute respiratory infection –  with fever ≥ 380 C (100.40F) and –  cough –  with onset within […]

Drugs that cause QT prolongation Antiarrhythmic agents Class IA Class IA antiarrthymic drugs work by blocking sodium and potassium channels. Blocking sodium channels tend to shorten the action potential duration, while blocking potassium channels prolongs the action potential. When the drug concentration is at a low to normal concentration, the potassium channel blocking activity takes […]

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following: Conditions: • increased risk of bleeding due to clotting disorder • a change in blood platelet function • a hemorrhage in the brain • bleeding within the skull • uterine fibroids • breast cancer • cancer […]

Released from KMC Once covid is diagnosed get a baseline CBP, LFT, RFT, CRP, d Dimer, IL6 (if available), LDH, Ferritin, Trop T, ECG, baseline CXR and CT chest. Ask for replication score in RT PCR test. It indicates how infective you are for other people. Any score above 25 is generally non infectious especially […]

– The Liangs, Bangalore August 2020 there is a volcano of info on dealing with Covid …..      But most of them is about the patient as an individual. Unfortunately, the reality is ….. …..Covid is infecting entire households, not just individuals. This is especially the case in India where it […]

M3 India Newsdesk Aug 14, 2020 A A A Dr. Sundeep Mishra in his exclusive COVID-19 series for M3 India details on the role of micronutrients and their supportive role in prevention and treatment of the infection. He also provides his opinion on herbal supplements being marketed as immunity boosters. For our comprehensive coverage and […]

Must read it! Written by Omer Khalid , a Paki writer, well read and based at UK. *India as a Hindu Rashtra?* -Khalid Umar (The author is originally from Pakistan and works as Barrister in UK. Is widely read. Forwarded from his FB account) —————————————- It is alleged that Narendra Modi/BJP want to make India […]

Experts from Charité — Universitätsmedizin Berlin, the University of Bonn, the German Center for Neurodegenerative Diseases (DZNE), the Helmholtz Centre for Infection Research (HZI) and the German Center for Infection Research (DZIF), along with colleagues from a nationwide research network, present these findings in the scientific journal Cell. Most patients infected with the coronavirus SARS-CoV-2 […]

Get three issues of BBC Science Focus Magazine for only £5 Viruses give us infections from the common cold to COVID-19 and AIDS. But research shows that they may also have played a key role in shaping the evolution of Homo sapiens. Coronavirus, Zika, Ebola, flu, even the boring old common cold – we’re all […]

Are humans still evolving? For much of nature, natural selection and ‘survival of the fittest’ still play a dominant role; only the strongest can survive in the wild. As little as a few hundred years ago, the same was true for humans, but what about now?  Nowadays, with the availability of better healthcare, food, heating […]

This review aims to highlight the historical hallmarks in the development of the concepts of seizures and epilepsy. It begins with a discussion of seizure semiology and terminology, followed by the pathophysiology of seizures. We then discuss the definition of epilepsy, its etiologies, and ultimately classification schemes. Each section starts with our current views and […]

Part II by Dr. Donald Perry Dr. Perry welcomes your comments and questions. Please email him at canopy evolution at gmail.com The fruits of our creativity – music, dance, mathematics, technology, and our awareness of the universe – are the result of evolutionary events that occurred in the murky depths of humanity’s distant past. Where and why this creative mind […]

and The Mask Matrix ©️ Dr. Rajas Deshpande Thousands of Indians, both rich and poor, are helping out each other during this pandemic. Many employers, from large companies to even lower middle class, are paying their employees for months now, without any income. While I am very proud of this humanity among the masses, there […]

Coronavirus Symptoms: There Are Six Different Types Of COVID Infections, Finds Study TIMESOFINDIA.COM | Last updated on – Aug 6, 2020, 10:49 IST 01/13Six different ways COVID-19 could affect you, study finds COVID-19 cases have breached the 18 million mark globally and there’s still a lot that remains unknown about the spread of the viral […]

http://www.americasfrontlinedoctors.com Introduction: General Consensus HCQ is safe………………………………………………………1 Rheumatologists Cardiologists Ophthalmologists Safety Studies …………………………………………………………………………………………………….4 2000-2020 (twenty years) study FDA Database (fifty years) CDC Statement American Heart Association Efficacy Studies (sample) ……………………………………………………………………………………7 February 19, 2020 March 4, 2020 March 20, 2020 March 22, 2020 March 22, 2020 April 11, 2020 April 13, 2020 April 17, 2020 April […]

*We were pressured by big pharma companies to publish series o*We were pressured by big pharma companies to publish series of spurious negative research reports against HydroxyChloroquine* 👇🏼 Editors of The Lancet and the New England Journal of Medicine: Pharmaceutical Companies are so Financially Powerful They Pressure us to Accept Papers Health Impact News Editors […]

 News Release MEDIA CONTACT: Kaitlin Meiser +1-908-938-3209 KMeiser3@its.jnj.com INVESTOR CONTACT: Janssen Announces U.S. FDA Approval of SPRAVATO® (esketamine) CIII Nasal Spray to Treat Depressive Symptoms in Adults with Major Depressive Disorder with Acute Suicidal Ideation or Behavior • SPRAVATO® is the first and only approved antidepressant medication shown to begin improving depressive symptoms with […]

Having scored 97% (10th), 97.58% (12th), 96.2% (UG) and have cracked GATE-19 and CAT-19 exam, I guess I’m eligible to answer this question. I’ll jump straight into some cool revision hacks that would help you secure exceptional returns in your grades. Best time for revision: I generally prefer the morning (4AM to 7AM) before the […]

Doctor 2025 ©️ Dr. Rajas Deshpande The whole family was happily relishing the desserts after a sumptuous dinner, when Mr. Shah suddenly went blank. His eyes rolled up, and he started having violent movements of his body. His daughter Amira shouted “Mom, call the emergency ambulance number” and tried to comfort her father who was […]

A new study found that COVID-19 symptoms come in six different “clusters,” which may help predict which patients are more at risk and in need of respiratory support. For the study, researchers used a machine learning algorithm to analyze data from more than 1,600 patients in the U.S. and the U.K. who had tested positive […]

Evidence is accumulating to suggest that preoccupation with Covid-19 is resulting in collateral damage to persons with other health conditions. What has been the impact of Covid-19 on pregnancy? This question was examined by Khalil et al (2020) at St George’s University Hospital, London, UK. These authors extracted data for pregnancy outcomes during 2 periods: […]

When the Covid-19 vaccine is ready, it would be interesting to see how it is distributed. One expects that the vaccine would reach citizens in the country of development first, in the rich countries next, and in the poorest countries last. Within a country, political and administrative leaders, the ultra rich, healthcare workers, and the […]

Vaccine freeloaders are persons who do not get vaccinated but who nevertheless reap the benefits of vaccination. The benefits of freeloading arise when the rest of the population is vaccinated and immune; then, the disease does not spread, and so the freeloaders do not contract the disease (Rashid et al, 2012). The desire to reap […]

TAKE-HOME MESSAGE This article corrects two misconceptions: that herd immunity can be represented by a single number, and that achieving herd immunity assures safety. ======================== THE SYNERGY TIMES ======================== Jul 30, 2020: Vol 20 No 90 It is popularly believed that herd immunity is a fixed number for a disease. It is also believed that […]

Jul 21, 2020: Vol 20 No 88 Every other day, somebody, somewhere in the world, presents a new mathematical model of how much worse the pandemic is going to get, or perhaps when the pandemic will end. Nobody can see into the future. So why should we believe these models any more than we believe […]

Jul 31, 2020: Vol 20 No 91 For how long does immunity against Covid-19 last in a person who has suffered and recovered from the disease? Experts say that nobody knows. This is actually untrue because it is now possible to make an educated guess. Consider: The disease originated in China in December 2019. It […]

• VERY INTERESTING OBSERVATIONS • • Covid-19 was first considered to be a viral pneumonia, but now it is known as a mysterious virus, which is predictably unpredictable. • It spares joints and larynx, so no joint involvement or hoarseness of voice; also, no lymph nodes involvement. • Covid-19 was earlier believed to be non-inflammatory, […]

Gender Dysphoria Gender dysphoria involves a conflict between a person’s physical or assigned gender and the gender with which he/she/they identify. People with gender dysphoria may be very uncomfortable with the gender they were assigned, sometimes described as being uncomfortable with their body (particularly developments during puberty) or being uncomfortable with the expected roles of […]

Visit Osmosis.org HealthEd Alternative Career Paths for Med Students (Organized By Personality Type) Hafsa Omer Published on Jul 28, 2020. Updated on Jul 28, 2020. Ever wonder if a career in medicine is really right for you? Today on the Osmosis blog, OMEF Hafsa Sulaiman shares a humorous account of career prospects outside the clinic, […]

 Ll BRARYI ONL OXFORD NEUROLOGY LIBRARY Alzheimer’s Disease  ONL OXFORD NEUROLOGY LIBRARY Second edition Edited by Gunhild Waldemar Professor of Clinical Neurology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Director, The Danish Dementia Research Centre, Copenhagen, Denmark and Alistair Burns Professor of Old-Age Psychiatry, University of Manchester, Manchester, UK; […]

A biosafety level (BSL), or pathogen/protection level, is a set of biocontainment precautions required to isolate dangerous biological agents in an enclosed laboratory facility. The levels of containment range from the lowest biosafety level 1 (BSL-1) to the highest at level 4 (BSL-4). In the United States, the Centers for Disease Control and Prevention (CDC) […]

*TrueNAT* TrueNat is a chip-based, portable RT-PCR machine, originally developed as a portable diagnostic tool for tuberculosis by Goa-based startup Molbio Diagnostics. TrueNat machine can detect an enzyme (called RdRp) found in the RNA of the coronavirus SARS-CoV-2. On 19 May, the ICMR revised its testing guidelines to allow the use of the TrueNAT system […]

Reporting on diagnostic imaging studies revolves around being able to accurately describe what we are seeing on the images. There are a number of terms that we commonly use in our reports that you should understand, and that you should be able to use when asked to describe an image. Radiographs The formation of an […]

Dear Doctors, Interleukin 6 has been an analyte which till recently was rarely used in general clinical practice. IN these days of COVID 19 it is being widely used to detect IL storm and helps in deciding whether Tocilizumab therapy ought to be given. It has come to our notice that when tested immediately after […]

Sanjiv Agarwal Founder, Good Governance India Foundation Mumbai, India sanjiv@ggif.in Hon’ble Prime Minister, Jay Bhattacharya, MD, PhD Professor of Medicine Stanford University Stanford, California USA jay@stanford.edu   Thank you for inviting suggestions regarding Unlock 2.0 in your recent speech. In response to your invitation we are writing our suggestions in the form of this […]

< Research has shown how coronavirus is affecting the brain of those infected. Image: REUTERS/Callaghan O’Hare This article is published in collaboration with The Conversation 16 Jul 2020 Michael Zandi Consultant Neurologist and Honorary Associate Professor in Neurology, UCL • COVID-19 is known as a respiratory disease, causing damage to a patient’s lungs. • However, […]

It’s a Tuesday morning at 11.30 am. You are already 45 minutes behind. A 35 year old woman is referred to your neurology clinic with a nine month history of fatigue, dizziness, back pain, left sided weakness, and reduced mobility. Her general practitioner documents a hysterectomy at the age of 25, subsequent division of adhesions […]

Hydroxychloroquin is useful in prophylaxis of covid. It’s found that Those who are on Hydroxychloroquin either don’t get covid or even if they get the disease runs a milder course in them. Proper PPE kit is must in covid ward .Also poper Donning & Doffing is required. Good infection control protocol should be in place. […]

Human medical trials have begun on severely ill COVID-19 patients using low-doses of radiation. The first results on a very small group were published this week in a non-peer-reviewed journal that exists to get critical results out quickly to the scientific and medical community. The results were quite extraordinary. Researchers at Emory University Hospital, led […]

The Clinical Diagnosis and Treatment for New Coronavirus Pneumonia Fanjun Cheng Yu Zhang Editors  1 3                                       […]

All the doctors here, please believe that you have no less brain than a lawyer. Consider the following facts: 1. CPA 1986 did not have healthcare included in the Letter (text) of the law. The text of the law in terms of definition of services remains same in CPA 2019. 2. SC interpreted CPA 1986 […]

There will be days when you wake up in the morning and ask the universe – why did I choose this profession? Most people who’re doctors are those who start reading for the highly competitive medical entrance after their 10th boards (some start earlier but I believe one should enjoy their childhood instead of running […]

There are 219 virus species that are known to be able to infect humans. The first of these to be discovered was yellow fever virus in 1901, and three to four new species are still being found every year. Extrapolation of the discovery curve suggests that there is still a substantial pool of undiscovered human […]

 History of professional etiquette Hospitals as we know them didn’t exist until the first Muslim-built “bimaristan” was established in Baghdad in 9th AD. Till late 19th century AD, doctors occupied a fairly low status in the society. From Roman times and throughout the European middle ages, doctors were subjected to and endured any indignity […]

I am a person who has returned home after recovering from corona. After returning home, I see in the news that corona affected patient cannot be admitted to hospital and is leaving this world at last. It is a very sad and tragic event. So I would like to share my experience with hospitalization. I […]

�© Dr. Rajas Deshpande “Screw this satisfaction. Dump this happiness. Can you try to understand that I am fed up of both?” said Dr. Sahil. He was one of the busiest and most respected specialist in our town. Surprised at a superspecialist friend speaking this, still impressed by his ability to identify and speak the […]

Technical Bulletin May, 2020 Revision 4 Comparison of FFP2, KN95, and N95 and Other Filtering Facepiece Respirator Classes                          Description Filtering facepiece respirators (FFR), which are sometimes called disposable respirators, are […]

(VERSION 3.0) DISCLAIMER: This Recommendation is derived from the prevailing trials published and collation of various guidelines. These guidelines would change with the evolving evidences DEFINITIONS: • ILI is defined as one with acute respiratory infection –  with fever ≥ 380 C (100.40F) and –  cough –  with onset within last 10 days • SARI […]