Government of India PIB
Press Briefing
11th June 2020
1
Cases per Lakh Population amongst the Lowest in the World
800 700 600 500 400 300 200 100
746.8
  
91.67 93.2
204.1
209.5
220.6
332.8 230.9
338.3
425.9 389.6
589.5 517.5
605.7
 
20.77
0
World India Mexico Turkey Iran Germany France Brazil Russia Italy UK Spain US Peru Chile

as per WHO Situation Report 142 dated 10th June, 2020
2
Death per Lakh Population – Amongst the Lowest in the World
70 60 50 40 30 20 10
0
60.2 56.3
  
5.23
10.0 4.4
10.4 5.6
10.9
58.0

17.5 11.9
16.9
44.8 33.5

0.59
                
as per WHO Situation Report 142 dated 10th June, 2020
3
 
Sero-surveillance to monitor the
trend of SARS-CoV-2 infection
transmission
COVID serosurvey
• What is serological survey?
• Blood samples collected from general population and tested for IgG antibodies
• IfapersonisIgGpositive,itmeanstheywereinfectedwithSARS-CoV-2inthepast
• Serosurveys are expected to answer the following questions
• What percentage of the general population has been infected by the virus?
• Who are at higher risk of getting infection?
• Which are the areas where containment efforts need to be strengthened?

Serosurvey for COVID
• ICMR conducted the first serosurvey in May 2020
• In collaboration with state health departments, NCDC, and WHO India
• Serosurvey had 2 parts
• PART I: Estimate fraction of population who has been infected with SARS-
CoV-2 in general population (COMPLETED)
• PART II: Estimate fraction of population who has been infected with SARS- CoV-2 in containment zones of hotspot cities (ONGOING)
     
Data and blood sample collection
• Data collection
• Socio-demographic details
• History of respiratory symptoms
• Written informed consent and ethics clearance
• Blood sample collection
• 3-5 ml of blood sample
• Laboratory investigations
• Sera tested for IgG antibodies, infection using COVID KAVACH ELISA

PART I: Population based serosurvey in districts
• Districts into four groups based on number of reported COVID-19 cases (incidence)
• Zero cases
• Low incidence
• Medium incidence • High incidence
• Selected minimum 15 districts from each group
• 400 individuals from each district
• Selected 10 villages/urban wards randomly • From each village/ward, enrolled 40 adults
• Only one adult enrolled from each household
 
Selection of districts & individuals surveyed
Stratum
Total no. of districts
Districts selected
No. of clusters selected
No. of clusters in urban area (%)
No. of households visited **
No. of individuals enrolled ** (% response)
Zero cases*
233
15
150
16 (11.4)
5886
5614 (95.4)
Low*
229
22
220
42 (21.0)
8352
8022 (96.0)
Medium*
84
16
160
48 (32.0)
6917
5980 (86.5)
High*
190
18
180
70 (41.2)
7440
6784 (91.2)
Total
736
83
770
176 (26.7)
28,595
26400 (92.3)

*Based on incidence of reported COVID cases as on 25 April 2020 **Data for 65 districts completed
Results
• 0.73% of the population in these districts had evidence of past exposure to SARS- CoV-2
• Lockdown/containment has been successful in keeping it low & preventing rapid spread
• However, it means that a large proportion of the population is still susceptible
• Risk is higher in Urban (1.09); Urban Slums (1.89) times higher than rural areas
• Infection fatality rate is very low 0.08%
• Infection in containment zones were found to be high with significant variations (still ongoing)
    
Conclusion: Way forward…
• Since, large proportion of the population is susceptible and infection can spread
• Non Pharmacological Interventions such as physical distancing, use of face
mask/cover, hand hygiene, cough etiquette must be followed strictly
• Urban slums highly vulnerable for the spread of infection
• Local lockdown measures need to continue as already advised by GOI
• High risk groups: Elderly, chronic morbidities, pregnant women & children less 10 years of age need to be protected
• Efforts to limit the scale and spread of the disease will have to be continued by strong implementation of containment strategies by the states
• The states cannot lower their guard & need to keep on implementing effective surveillance and containment strategies
  










